Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells.
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DOI: 10.1016/j.bbrc.2019.06.156
Abstract: Tyrosine hydroxylase (TH), which catalyzes the conversion of l-tyrosine to l-DOPA, is the rate-limiting enzyme in the biosynthesis of catecholamines. It is well known that both α-synuclein and 14-3-3 protein family members bind to the… read more here.
Keywords: nt5dc2 sirna; pc12d; regulation nt5dc2; tyrosine hydroxylase ... See more keywords