Articles with "pc190723" as a keyword



A mechanism of salt bridge–mediated resistance to FtsZ inhibitor PC190723 revealed by a cell-based screen

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Published in 2022 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e22-12-0538

Abstract: Bacterial cell division proteins, especially the tubulin homolog FtsZ, have emerged as strong targets for developing new antibiotics. Here, we have utilized the fission yeast heterologous expression system to develop a cell-based assay to screen… read more here.

Keywords: pc190723; cell based; cell; resistance ... See more keywords