Prostate cancer cells modulate the differentiation of THP‐1 cells in response to etoposide and TLR agonists treatments
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11410
Abstract: The aim of this study was to determine the polarization of macrophages in the tumor microenvironment, as well as the effect of soluble factors secreted from these polarized macrophages on etoposide‐induced cancer cell apoptosis. We… read more here.
Keywords: pc3 cells; tlr agonists; cancer cells; cancer ... See more keywords
MicroRNA-32 Suppression: its Effects on Prostate Cancer Cells’ Capability to Proliferate and Migrate
Sign Up to like & getrecommendations! Published in 2022 at "Drug Research"
DOI: 10.1055/a-1977-8848
Abstract: Abstract Introduction This paper sought to scrutinize the role of microRNA-32 (miR-32) on the growth and migration as well as on the expression of metastatic genes in PC3 cells of prostate cancer in vitro. Methods… read more here.
Keywords: pc3 cells; microrna; prostate cancer; suppression ... See more keywords
Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2048133
Abstract: Abstract Prostate cancer (PC) is emerging as one of the leading causes of mortality and morbidity worldwide. Curcumin (CUR) is a well-known phytochemical, and scorpion venom (SV) is a natural peptide with proven anticancer properties.… read more here.
Keywords: prostatic cancer; human prostatic; pc3 cells; scorpion venom ... See more keywords
Novel piperidine derivatives as colchicine binding site inhibitors induce apoptosis and inhibit epithelial-mesenchymal transition against prostate cancer PC3 cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2020.1783664
Abstract: Abstract Tubulin polymerisation inhibitors that target colchicine binding site were powerful anticancer agents. Although along the years many colchicine binding site inhibitors (CBSIs) have been reported, few piperidine derivatives were identified as CBSIs. In this… read more here.
Keywords: pc3 cells; binding site; piperidine derivatives; colchicine binding ... See more keywords
IL-6 As a Potential Cell Released Marker of Prostate Cancer Cell Death
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-116076
Abstract: Introduction: Interleukin 6 (IL-6) is proinflammatory cytokine which is produced by cell when Nod-like receptors (NLRs) are activated. Increased production of IL-6 was shown to promote tumor growth and metastasis.Therefore, it could be suggested that… read more here.
Keywords: prostate; pc3 cells; cell death; culture ... See more keywords
In Vitro Pro-apoptotic and Anti-migratory Effects of Ficus deltoidea L. Plant Extracts on the Human Prostate Cancer Cell Lines PC3
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00895
Abstract: This study aims to evaluate the in vitro cytotoxic and anti-migratory effects of Ficus deltoidea L. on prostate cancer cells, identify the active compound/s and characterize their mechanism of actions. Two farmed varieties were studied,… read more here.
Keywords: pc3 cells; cell; plant extracts; cancer ... See more keywords
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11112119
Abstract: In spite of extensive successes, cancer recurrence after radiation treatment (RT) remains one of the significant challenges in the cure of localized prostate cancer (PCa). This study focuses on elucidating a novel adaptive response to… read more here.
Keywords: cancer; clone 695; pc3 cells; production ... See more keywords
Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20112613
Abstract: Acute administration of a high level of extracellular citrate displays an anti-proliferative effect on both in vitro and in vivo models. However, the long-term effect of citrate treatment has not been investigated yet. Here, we… read more here.
Keywords: pc3; citrate; pc3 cells; long term ... See more keywords
Bioassay-Guided Identification of the Antiproliferative Compounds of Cissus trifoliata and the Transcriptomic Effect of Resveratrol in Prostate Cancer Pc3 Cells
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26082200
Abstract: The bioassay-guided fractionation of a CHCl3-MeOH extract from the stems of Cissus trifoliata identified an active fraction against PC3 prostate cancer cells. The treatment for 24 h showed an 80% reduction in cell viability (p… read more here.
Keywords: pc3; bioassay guided; pc3 cells; prostate cancer ... See more keywords
Ethanol extracts of Hizikia fusiforme induce apoptosis in human prostate cancer PC3 cells via modulating a ROS-dependent pathway
Sign Up to like & getrecommendations! Published in 2020 at "Asian Pacific Journal of Tropical Biomedicine"
DOI: 10.4103/2221-1691.275422
Abstract: Objective: To investigate whether ethanol extracts of Hizikia fusiforme could induce apoptosis in human prostate cancer PC3 cells. Methods: Cell viability was evaluated using 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide. Apoptosis and mitochondrial membrane potential (MMP) were measured… read more here.
Keywords: apoptosis; pc3 cells; hizikia fusiforme; extracts hizikia ... See more keywords
Down-regulation of F-actin and paxillin by N-(3-(1Htetrazol- 1-yl)phenyl) isonicotinamide derivative inhibits proliferation of prostate cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v19i7.8
Abstract: Purpose: To investigate the effect of N-(3-(1H-tetrazol-1-yl)phenyl) isonicotinamide derivative (TPIN) on prostate cancer cells, and the mechanism involved. Methods: The cytotoxicity of TPIN in DU145 and PC3 cells was determined using Cell Counting Kit-8, while… read more here.
Keywords: prostate; cancer cells; prostate cancer; pc3 cells ... See more keywords