Optimization and characterization of a bone culture model to study prostate cancer bone metastasis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cancer therapeutics"
DOI: 10.1158/1535-7163.mct-21-0684
Abstract: Nearly 90% of patients with advanced prostate cancer (PCa) manifest bone metastases. Distinct from the osteolytic metastasis mostly observed in other cancer types, PCa bone metastasis is typically more osteoblastic, which is relatively understudied due… read more here.
Keywords: metastasis; prostate cancer; bone; bone metastasis ... See more keywords
microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.988794
Abstract: Objective To investigate the effects of miRNA-145-5p on the tumor development and progression of prostate cancer (Pca) bone metastasis. Methods Levels of miRNA-145-5p were assessed by real-time quantitative PCR in PC3 (bone metastatic Pca cells),… read more here.
Keywords: mirna 145; prostate cancer; bone; bone metastatic ... See more keywords