Proteomic Identification of Small Extracellular Vesicle Proteins LAMB1 and Histone H4 for Prostate Cancer Diagnosis and Risk Stratification
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202402509
Abstract: Diagnosis and stratification of prostate cancer (PCa) patients using the prostate‐specific antigen (PSA) test is challenging. Extracellular vesicles (EVs), as a new star of liquid biopsy, has attracted interest to complement inaccurate PSA screening and… read more here.
Keywords: diagnosis; cancer; stratification; risk ... See more keywords
Enhanced vascular inflammation in patients with advanced prostate cancer receiving hormone therapy
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-025-07409-6
Abstract: While blocking androgen production and action effectively slows prostate cancer (PCa) progression, it is associated with significant side effects, including an increased risk of cardiovascular disease. Inflammatory activity within atherosclerotic arteries can be assessed using… read more here.
Keywords: hormone therapy; fdg pet; pca patients; 18f fdg ... See more keywords
XPNPEP2 is associated with lymph node metastasis in prostate cancer patients
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45245-5
Abstract: As we reported in our previous studies, TMTP1, a tumor-homing peptide, selectively targets highly metastatic tumors and their metastatic foci. Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical… read more here.
Keywords: prostate; pca patients; prostate cancer; metastasis ... See more keywords
Lifestyle interventions to alleviate side effects on prostate cancer patients receiving androgen deprivation therapy: a meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Japanese Journal of Clinical Oncology"
DOI: 10.1093/jjco/hyy101
Abstract: Background Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) are prone to suffer a series of potential side effects, including metabolic change, declining physical strength and worsening fatigue. Recent studies found that the change… read more here.
Keywords: pca patients; lifestyle interventions; prostate cancer; side effects ... See more keywords
Serum ACSL4 levels in prostate cancer patients and its relationship between patient prognosis: A prospective observational study
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000039119
Abstract: In this prospective observational study, our objective was to investigate the serum levels of Acyl-CoA synthetase long-chain family member 4 (ACSL4) in prostate cancer (PCa) patients and examine its association with other serum biomarkers, and… read more here.
Keywords: acsl4 levels; observational study; serum acsl4; pca patients ... See more keywords
Survival Analysis and a Novel Nomogram Model for Progression-Free Survival in Patients with Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6358707
Abstract: Background This study sought to perform a survival analysis and construct a prognostic nomogram model based on the Gleason grade, total prostate-specific antigen (tPSA), alkaline phosphate (ALP), and TNM stage in patients with prostate cancer… read more here.
Keywords: survival; analysis; tpsa alp; nomogram model ... See more keywords
Abstract 4595: STAT-3 chemical inhibition modulates decidual-like polarization in NK cells from PCa patients and restore their anti-tumor activities
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4595
Abstract: Introduction. Natural Killer (NK) cells are innate lymphoid cells involved in tumour recognition/elimination. NK cells are altered in their phenotype and functions in diverse tumors, including prostate cancer (PCa). We demonstrated that PCa circulating NK… read more here.
Keywords: cell; pca tanks; pca patients; pca ... See more keywords
Abstract 5351: The landscape of somatic mutations and copy-number alterations in the Indian Cohort of Prostate Cancer Patients
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-5351
Abstract: In India, prostate cancer (PCa) has the third highest incidence rate among males and is often diagnosed at the advanced stage. PCa is known to be molecularly heterogeneous, and an in-depth characterization of its subtypes… read more here.
Keywords: cancer; cohort; pca; pca patients ... See more keywords
Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Epigenetics"
DOI: 10.1186/s13148-018-0490-3
Abstract: BackgroundPeriprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling… read more here.
Keywords: pca patients; excess adiposity; methylation; adiposity ... See more keywords
Evaluation of gastrin-releasing peptide receptor, prostate-specific membrane antigen, and neurotensin receptor 1 as potential biomarkers for accurate prostate cancer stratified diagnosis
Sign Up to like & getrecommendations! Published in 2024 at "EJNMMI Research"
DOI: 10.1186/s13550-024-01116-3
Abstract: Studies on single-target PET imaging of gastrin-releasing peptide receptor (GRPR), prostate-specific membrane antigen (PSMA), or neurotensin receptor 1(NTR1) have been reported. However, the performance of these three targets in the progression of PCa remains unclear.… read more here.
Keywords: receptor; prostate; pca; pca patients ... See more keywords
Long-term androgen deprivation therapy (ADT) with leuprorelin and quality of life in patients with advanced prostate cancer (PCa).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.268
Abstract: 268Background: LHRH analogs are the gold standard for treatment of patients with hormone-sensitive advanced PCa. In this study, we investigated the quality of life (QoL) of PCa patients under long-term treatment with leuprorelin acetate in… read more here.
Keywords: pca patients; long term; treatment; pca ... See more keywords