Association between age‐related reductions in testosterone and risk of prostate cancer—An analysis of patients' data with prostatic diseases
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Cancer"
DOI: 10.1002/ijc.30882
Abstract: The relationship between serum total testosterone and prostate cancer (PCa) risk is controversial. The hypothesis that faster age‐related reduction in testosterone is linked with increased PCa risk remains untested. We conducted our study at a… read more here.
Keywords: risk; age related; testosterone; pca risk ... See more keywords
Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Prostate Cancer and Prostatic Diseases"
DOI: 10.1038/pcan.2017.25
Abstract: Background:Prostate cancer (PCa) is the fifth leading cause of cancer-related deaths worldwide. Many epidemiological studies have investigated the association between prostate cancer and lycopene, however, results have been inconsistent. This study aims to determine the… read more here.
Keywords: risk; circulating lycopene; dietary circulating; pca risk ... See more keywords
Spironolactone use is associated with lower prostate cancer risk: a population-wide case-control study
Sign Up to like & getrecommendations! Published in 2020 at "Prostate Cancer and Prostatic Diseases"
DOI: 10.1038/s41391-020-0220-8
Abstract: Background Spironolactone, a cheap effective diuretic used to manage hypertension and heart failure, also has anti-androgenic effects through its non-selective binding to steroid receptors, and hence may affect prostate cancer (PCa) risk. This study investigated… read more here.
Keywords: pca risk; risk; spironolactone; prostate cancer ... See more keywords
The causal effect of serum amino acids on the risk of prostate cancer: a two-sample mendelian randomization study
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DOI: 10.1038/s41598-024-80986-y
Abstract: Prostate cancer (PCa) is the second most common malignancy affecting men globally. Recent advances in metabolomics have highlighted significant alterations in specific amino acid (AA) metabolism linked to PCa, indicating their potential utility in diagnosis… read more here.
Keywords: serum; prostate cancer; risk; causal ... See more keywords
Abstract 3599: Proteomic risk factors for prostate cancer: A case-cohort study in EPIC
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DOI: 10.1158/1538-7445.am2025-3599
Abstract: Prostate cancer (PCa) is the most prevalent cancer among men in Europe, yet its aetiology is poorly understood. Proteins contribute to the development of carcinogenesis and are also the target of most pharmacological interventions. The… read more here.
Keywords: cancer; cohort; risk; study ... See more keywords
Associations between genetically predicted concentrations of plasma proteins and the risk of prostate cancer
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DOI: 10.1186/s12885-024-12659-y
Abstract: Prostate cancer (PCa) is a leading cause of cancer-related death in men. Understanding the proteomic landscape associated with PCa risk can provide insights into its molecular mechanisms and pave the way for potential therapeutic interventions.… read more here.
Keywords: cancer; genetically predicted; predicted concentrations; pca risk ... See more keywords
The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study
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DOI: 10.1371/journal.pmed.1003859
Abstract: Background Numerous epidemiological studies have investigated the role of blood lipids in prostate cancer (PCa) risk, though findings remain inconclusive to date. The ongoing research has mainly involved observational studies, which are often prone to… read more here.
Keywords: pca risk; prostate cancer; genetically predicted; lipids prostate ... See more keywords
Prediagnostic Plasma Nutrimetabolomics and Prostate Cancer Risk: A Nested Case–Control Analysis Within the EPIC Study
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DOI: 10.3390/cancers16234116
Abstract: Simple Summary Previous studies using a metabolomics approach in relation to prostate cancer (PCa) risk assessment have focused on endogenous metabolism. As far as we know, the associations between circulating metabolites derived from exogenous sources,… read more here.
Keywords: cancer; prostate cancer; risk; study ... See more keywords