Association Between Combined TMPRSS2: ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.0177
Abstract: Importance Potential survival benefits from treating aggressive (Gleason score, ≥7) early-stage prostate cancer are undermined by harms from unnecessary prostate biopsy and overdiagnosis of indolent disease. Objective To evaluate the a priori primary hypothesis that… read more here.
Keywords: prostate; biopsy; pca3; prostate cancer ... See more keywords
PCA3 como biomarcador de segunda línea en un programa de screening oportunista prospectivo, aleatorizado y controlado
Sign Up to like & getrecommendations! Published in 2017 at "Actas Urologicas Espanolas"
DOI: 10.1016/j.acuro.2016.10.008
Abstract: Resumen Objetivos Determinar el comportamiento del PCA3 como un marcador de segunda linea en un programa de cribado oportunista de cancer de prostata (CaP) y su comparacion con la calculadora de riesgo 3 del cribado… read more here.
Keywords: biomarcador segunda; del; como biomarcador; pca3 ... See more keywords
Role of PCA3 and SelectMDx in the optimization of active surveillance in prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Actas urologicas espanolas"
DOI: 10.1016/j.acuroe.2020.10.013
Abstract: INTRODUCTION & OBJECTIVES A not negligible percentage of patients included in active surveillance (AS) for low and very low risk prostate cancer (PCa) are reclassified in the confirmatory biopsy or have disease progression during follow-up.… read more here.
Keywords: active surveillance; pca3; role pca3; prostate cancer ... See more keywords
Electrochemical and optical detection and machine learning applied to images of genosensors for diagnosis of prostate cancer with the biomarker PCA3
Sign Up to like & getrecommendations! Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2020.121444
Abstract: Abstract The development of simple detection methods aimed at widespread screening and testing is crucial for many infections and diseases, including prostate cancer where early diagnosis increases the chances of cure considerably. In this paper,… read more here.
Keywords: detection; machine learning; pca3; prostate cancer ... See more keywords
A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16700-y
Abstract: Short tandem repeats (STRs) are repetitive sequences of a polymorphic stretch of two to six nucleotides. We hypothesized that STRs are associated with prostate cancer development and/or progression. We undertook RNA sequencing analysis of prostate… read more here.
Keywords: prostate; pca3; prostate cancer; cancer risk ... See more keywords
Diagnostic performance of PCA3 and hK2 in combination with serum PSA for prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012806
Abstract: Objectives: The prostate cancer gene 3 (PCA3), human kallikrein 2, and miRNA-141 are promising prostate cancer (Pca) specific biomarkers. Our aim was to evaluate the detection of PCA3, human glandular kallikrein 2 (hk2), and miRNA-141… read more here.
Keywords: pca3; psa; prostate cancer; pca3 hk2 ... See more keywords
The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.27284
Abstract: Prostate cancer antigen 3 (PCA3) is an overexpressed prostate long non-coding RNA (lncRNA), transcribed from an intronic region at the long arm of human chromosome 9q21–22. It has been described that PCA3 modulates prostate cancer… read more here.
Keywords: pca3; biomarker; prostate cancer; expression ... See more keywords
Detection of Prostate Cancer Biomarker PCA3 by using Aptasensors.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220607162250
Abstract: BACKGROUND Prostate cancer cells have very high PCA3 messenger RNA levels, which turns it into one of the new biomarkers for prostate cancer prognosis and diagnosis. OBJECTIVE Our goal here is to development a new… read more here.
Keywords: pca3; prostate cancer; cancer; detection prostate ... See more keywords