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   Articles with "pcat1" as a keyword



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Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions

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recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2120534119

Abstract: Significance Recent advances in cryo-electron microscopy (cryo-EM) enabled us to determine multiple structures from the same sample. At equilibrium, the Boltzmann distribution law can be applied to identify the lowest energy state of the protein.… read more here.

Keywords: peptidase containing; pcat1; transporter; microscopy ... See more keywords
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The Cerna Network of Long Non-Coding RNA PCAT1/Mir-128-3p/SEC61A1 In Colon Cancer Cell Proliferation and Invasion.

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recommendations! Published in 2023 at "Protein and peptide letters"

DOI: 10.2174/0929866530666230125110222

Abstract: BACKGROUND Colon cancer (CC) remains a highly malignant cancer, with long non-coding RNAs (lncRNAs) associated with its molecular etiology. OBJECTIVE This study sought to investigate the mechanism of lncRNA prostate cancer-associated transcript 1 (lncRNA PCAT1)… read more here.

Keywords: cell proliferation; pcat1; proliferation invasion; lncrna pcat1 ... See more keywords
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PCAT1 promotes the proliferative and migratory potentials of ovarian cancer via targeting NEK2.

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recommendations! Published in 2019 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201910_19133

Abstract: OBJECTIVE The aim of this study was to clarify the potential role of PCAT1 in the occurrence and development of ovarian cancer (OC). PATIENTS AND METHODS Expression levels of PCAT1 and NEK2 in OC tissues… read more here.

Keywords: pcat1; proliferative migratory; expression; ovarian cancer ... See more keywords
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TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.862015

Abstract: Recent evidence has shown that the induction of ferroptosis is a new therapeutic strategy for advanced prostate cancer (PCa) when used as a monotherapy or in combination with second-generation antiandrogens. However, whether ferroptosis inducers are… read more here.

Keywords: prostate cancer; pcat1; pca; docetaxel resistant ... See more keywords
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Long non‑coding RNA PCAT1 sponges miR‑134‑3p to regulate PITX2 expression in breast cancer.

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recommendations! Published in 2022 at "Molecular medicine reports"

DOI: 10.3892/mmr.2022.12591

Abstract: Breast cancer (BC) is the most prevalent cancer among women. Long non‑coding (lnc)RNAs and microRNAs (miRs) both regulate the expression of key genes in tumorigenesis. The present study aimed to explore the molecular mechanism of… read more here.

Keywords: cell; pcat1; mir 134; expression ... See more keywords