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Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6010
Abstract: Pheochromocytomas (PCCs) are rare neuroendocrine tumors derived from the chromaffin cells of the adrenal medulla. When these tumors have an extra-adrenal location, they are called paragangliomas (PGLs) and arise from sympathetic and parasympathetic ganglia, particularly…
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Keywords:
review;
pccs pgls;
diagnosis treatment;
paragangliomas ... See more keywords
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Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.01.001
Abstract: We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that PCCs/PGLs are driven by diverse alterations affecting multiple genes and pathways. Pathogenic germline mutations occurred in…
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Keywords:
pccs pgls;
molecular characterization;
characterization pheochromocytoma;
comprehensive molecular ... See more keywords
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Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00079
Abstract: Pheochromocytoma (PCC) and paraganglioma (PGL) are rare neuroendocrine tumors associated with high cardiovascular morbidity and variable risk of malignancy. The current therapy of choice is surgical resection. Nevertheless, PCCs/PGLs are associated with a lifelong risk…
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Keywords:
cancer stem;
cells pheochromocytoma;
pccs pgls;
cancer ... See more keywords