Abstract 5883: Role of major facilitative folate transporters SLC19A1 and SLC46A1 in cyclic dinucleotide transport and STING signaling
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DOI: 10.1158/1538-7445.am2024-5883
Abstract: Activation of stimulator of interferon genes (STING) activates the transcription factor pIRF3, promoting gene transcription encoding type I interferons including IFNβ that stimulate broader immune responses. Targeting the STING pathway for cancer is especially compelling… read more here.
Keywords: transport; tet rfc; adu s100; pcft ... See more keywords
Regulation of folate transport at the mouse arachnoid barrier
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DOI: 10.1186/s12987-024-00566-0
Abstract: Folates are a family of B9 vitamins essential for normal growth and development in the central nervous system (CNS). Transport of folates is mediated by three major transport proteins: folate receptor alpha (FRα), proton-coupled folate… read more here.
Keywords: transport; folate; folate transport; pcft ... See more keywords