Polycomb‐mediated gene regulation in human brain development and neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22876
Abstract: The neocortex is considered the seat of higher cognitive function in humans. It develops from a sheet of neural progenitor cells, most of which eventually give rise to neurons. This process of cell fate determination… read more here.
Keywords: neurodevelopmental disorders; pcg; development; regulation human ... See more keywords
Primary congenital glaucoma: An updated review
Sign Up to like & getrecommendations! Published in 2019 at "Saudi Journal of Ophthalmology"
DOI: 10.1016/j.sjopt.2019.10.002
Abstract: Primary congenital glaucoma (PCG) is a rare disease affecting children early in life. PCG was considered untreatable with inevitable blindness. However, recent advances in biochemical and genetic studies, the introduction of new diagnostic tools, intraocular… read more here.
Keywords: glaucoma updated; pcg; congenital glaucoma; updated review ... See more keywords
Intercropping kura clover with prairie cordgrass mitigates soil greenhouse gas fluxes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64182-2
Abstract: Prairie cordgrass (PCG) ( Spartina pectinata Link) has a high tolerance to soil salinity and waterlogging, therefore, it can thrive on marginal lands. Optimizing the nitrogen (N) input is crucial to achieving desirable biomass production… read more here.
Keywords: kura clover; prairie cordgrass; pcg; soil ... See more keywords
A host–gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood–brain barrier integrity in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Tissue Barriers"
DOI: 10.1080/21688370.2022.2073175
Abstract: ABSTRACT The sequential activity of gut microbial and host processes can exert a powerful modulatory influence on dietary components, as exemplified by the metabolism of the amino acids tyrosine and phenylalanine to p-cresol by gut… read more here.
Keywords: pcg; barrier; brain; gut microbial ... See more keywords
Context dependent role of Pho binding sites in Polycomb complex recruitment in Drosophila.
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyad096
Abstract: Polycomb group (PcG) proteins maintain the silenced state of key developmental genes, but how these proteins are recruited to specific regions of the genome is still not completely understood. In Drosophila, PcG proteins are recruited… read more here.
Keywords: pho; pcg; recruitment drosophila; pho binding ... See more keywords
Robust Denoising of Phonocardiogram Signals using Time-Frequency Analysis and U-Nets
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Access"
DOI: 10.1109/access.2023.3280453
Abstract: Cardiovascular diseases are the cause of many deaths worldwide every day. Automated cardiac auscultation is a promising diagnosis method; however, one of its main disadvantages is that it is prone to receiving too much noise… read more here.
Keywords: phonocardiogram; time frequency; noise; pcg ... See more keywords
2-Phase Adiabatic Logic for Low-Energy and CPA-Resistant Implantable Medical Devices
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Consumer Electronics"
DOI: 10.1109/tce.2022.3141342
Abstract: Designing a low-energy and secure lightweight cryptographic coprocessor is the primary design constraint for modern wireless Implantable Medical Devices (IMDs). The lightweight cryptographic ciphers are the preferred cryptographic solution for low-energy encryption. This article proposes… read more here.
Keywords: low energy; medical devices; pcg; energy ... See more keywords
CYP1B1 and MYOC variants in neonatal-onset versus infantile-onset primary congenital glaucoma
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Ophthalmology"
DOI: 10.1136/bjophthalmol-2020-318563
Abstract: Objective To compare CYP1B1 and MYOC variants in a cohort of neonatal-onset (NO) and infantile-onset (IO) primary congenital glaucoma (PCG). Methods This prospective observational study included 43 infants with PCG (14 NO and 29 IO) presenting… read more here.
Keywords: pcg; cyp1b1 myoc; myoc variants; glaucoma ... See more keywords
Animal Model Contributions to Primary Congenital Glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Ophthalmology"
DOI: 10.1155/2022/6955461
Abstract: Primary congenital glaucoma (PCG) is an ocular disease characterized by congenital anterior segmental maldevelopment with progressive optic nerve degeneration. Certain genes, such as cytochrome P450 family 1 subfamily B member 1 and latent TGF-β-binding protein… read more here.
Keywords: model contributions; congenital glaucoma; pcg; animal model ... See more keywords
Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA- PCG pairs involved in intermediary metabolism
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0224644
Abstract: Polybrominated diphenyl ethers (PBDEs) were formally used as flame-retardants and are chemically stable, lipophlic persistent organic pollutants which are known to bioaccumulate in humans. Although its toxicities are well characterized, little is known about the… read more here.
Keywords: involved intermediary; pcg pairs; metabolism; intermediary metabolism ... See more keywords
Mutation screening of the CYP1B1 gene reveals thirteen novel disease-causing variants in consanguineous Pakistani families causing primary congenital glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0274335
Abstract: Background Primary congenital glaucoma (PCG) is a heterogeneous rare recessively inherited disorder prevalent in regions with high consanguinity. Disease phenotype is associated with increased intra ocular pressure and is a major cause of childhood blindness.… read more here.
Keywords: causing variants; disease; pcg; cyp1b1 gene ... See more keywords