Hierarchical recruitment of Polycomb complexes revisited
Sign Up to like & getrecommendations! Published in 2017 at "Nucleus"
DOI: 10.1080/19491034.2017.1363136
Abstract: ABSTRACT Polycomb Group (PcG) proteins epigenetically repress key developmental genes and thereby control alternative cell fates. PcG proteins act as complexes that can modify histones and these histone modifications play a role in transmitting the… read more here.
Keywords: polycomb; histone modifications; pcg complexes; hierarchical recruitment ... See more keywords
Know when to fold ‘em: Polycomb complexes in oncogenic 3D genome regulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.986319
Abstract: Chromatin is spatially and temporally regulated through a series of orchestrated processes resulting in the formation of 3D chromatin structures such as topologically associating domains (TADs), loops and Polycomb Bodies. These structures are closely linked… read more here.
Keywords: know fold; pcg complexes; genome regulation; fold polycomb ... See more keywords
Roles of Polycomb Complexes in the Reconstruction of 3D Genome Architecture during Preimplantation Embryonic Development
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13122382
Abstract: The appropriate deployment of developmental programs depends on complex genetic information encoded by genomic DNA sequences and their positioning and contacts in the three-dimensional (3D) space within the nucleus. Current studies using novel techniques including,… read more here.
Keywords: developmental programs; pcg; pcg complexes; roles polycomb ... See more keywords