The multiscale effects of polycomb mechanisms on 3D chromatin folding
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2019.1679082
Abstract: Abstract Polycomb group (PcG) proteins silence master regulatory genes required to properly confer cell identity during the development of both Drosophila and mammals. They may act through chromatin compaction and higher-order folding of chromatin inside… read more here.
Keywords: chromatin domains; chromatin folding; chromatin; pcg proteins ... See more keywords
Loss of Polycomb proteins CLF and LHP1 leads to excessive RNA degradation in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac216
Abstract: Polycomb-group (PcG) proteins are major chromatin complexes that regulate gene expression, mainly described as repressors keeping genes in a transcriptional silent state during development. Recent studies have nonetheless suggested that PcG proteins might have additional… read more here.
Keywords: polycomb; active genes; rna degradation; pcg proteins ... See more keywords
Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad336
Abstract: The Polycomb group (PcG) proteins are fundamental epigenetic regulators that control the repressive state of target genes in multicellular organisms. One of the open questions is defining the mechanisms of PcG recruitment to chromatin. In… read more here.
Keywords: crol; polycomb group; pcg proteins;
Differential Contributions of DNA-Binding Proteins to Polycomb Response Element Activity at the Drosophila giant Gene.
Sign Up to like & getrecommendations! Published in 2020 at "Genetics"
DOI: 10.1534/genetics.119.302981
Abstract: Polycomb-group (PcG) proteins utilize epigenetic mechanisms to maintain the transcriptional silence of target genes. Recruitment of Drosophila PcG proteins to target genes requires the presence of a Polycomb Response Element (PRE). Some PcG target genes,… read more here.
Keywords: drosophila; target genes; pcg; polycomb response ... See more keywords