The PCNA interaction motifs revisited: thinking outside the PIP-box
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DOI: 10.1007/s00018-019-03150-0
Abstract: Proliferating cell nuclear antigen (PCNA) is a cellular hub in DNA metabolism and a potential drug target. Its binding partners carry a short linear motif (SLiM) known as the PCNA-interacting protein-box (PIP-box), but sequence-divergent motifs… read more here.
Keywords: pcna; pcna interaction; pip box; affinity ... See more keywords
APIM-Mediated REV3L–PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells
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DOI: 10.3390/ijms20010100
Abstract: Proliferating cell nuclear antigen (PCNA) is essential for the organization of DNA replication and the bypass of DNA lesions via translesion synthesis (TLS). TLS is mediated by specialized DNA polymerases, which all interact, directly or… read more here.
Keywords: pcna; apim mediated; pcna interaction; tls ... See more keywords