Gut Microbiota Modulation by Inulin Improves Metabolism and Ovarian Function in Polycystic Ovary Syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202412558
Abstract: The management of metabolic disorder associated with polycystic ovary syndrome (PCOS) has been suggested as an effective approach to improve PCOS which is highly involved with gut microbiota, while the underlying mechanism is unclear. Here,… read more here.
Keywords: polycystic ovary; gut microbiota; inulin; pcos ... See more keywords
Lycopene Ameliorates Polycystic Ovary Syndrome in Rats by Inhibiting Ovarian Ferroptosis Through Activation of the AMPK/Nrf2 Pathway
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DOI: 10.1002/jbt.70158
Abstract: Lycopene (LYC) is an extremely powerful antioxidant with the potential to treat a range of diseases and to inhibit ferroptosis. This research aims to elucidate how LYC impacts polycystic ovarian syndrome (PCOS) and the action… read more here.
Keywords: ampk nrf2; ferroptosis; pcos; nrf2 pathway ... See more keywords
Improvement of oocyte in vitro maturation from mice with polycystic ovary syndrome by human mesenchymal stromal cell–conditioned media
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27380
Abstract: The outcome of in vitro maturation (IVM) in the patients with polycystic ovary syndrome (PCOS) is poor. Abnormal intraovarian paracrine interplay alters microenvironment for oocyte development through folliculogenesis and decreases developmental competence of oocytes in… read more here.
Keywords: pcos; oocyte; vitro maturation; maturation ... See more keywords
Gingival inflammation and leukocyte–endothelium cell interactions in women with polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Periodontology"
DOI: 10.1002/jper.24-0148
Abstract: Abstract Background Given the link between chronic inflammation and periodontal pathologies and increased cardiovascular risk, this study aims to investigate if gingivitis exacerbates the inflammatory response and subclinical atherosclerotic markers in women with polycystic ovary… read more here.
Keywords: polycystic ovary; adhesion; women polycystic; endothelium ... See more keywords
Thymoquinone improves folliculogenesis, sexual hormones, gene expression of apoptotic markers and antioxidant enzymes in polycystic ovary syndrome rat model
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.958
Abstract: Abstract Background Nowadays, polycystic ovary syndrome (PCOS) is a prevalent cause of infertility affecting women of reproductive age around the world. Thymoquinone is a natural antioxidant, derived from Nigella sativa. Objectives The current study aimed… read more here.
Keywords: thymoquinone; pcos; gene expression; polycystic ovary ... See more keywords
The impact of a standardized micronutrient supplementation on PCOS-typical parameters: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-019-05194-w
Abstract: PurposeTo evaluate whether a micronutrient supplementation preparation that includes a high amount of omega-3 unsaturated acids, other anti-oxidants and co-enzyme Q10 would have an impact on specific serum parameters in women with polycystic ovary syndrome… read more here.
Keywords: hormone; supplementation; randomized controlled; trial ... See more keywords
Serum zonulin level is not elevated in patients with polycystic ovary syndrome without metabolic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-019-05345-z
Abstract: Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship… read more here.
Keywords: polycystic ovary; pcos; cholesterol; metabolic syndrome ... See more keywords
Hypermethylation and down-regulation of vitamin D receptor (VDR) as contributing factors for polycystic ovary syndrome (PCOS): a case–control study from Kashmir, North India
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DOI: 10.1007/s00404-023-07326-9
Abstract: Background Polycystic ovarian syndrome (PCOS) is a prevailing endocrinopathy affecting a significant population of women of reproductive age across the globe. A myriad set of complex intertwined factors ranging from etiological, genetic, and epigenetic reasons… read more here.
Keywords: methylation; vitamin; pcos; gene ... See more keywords
Genome-wide association study (GWAS) identified PCOS susceptibility variants and replicates reported risk variants
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DOI: 10.1007/s00404-024-07400-w
Abstract: Genetic predisposition and environmental factors are considered risk factors for polycystic ovary syndrome (PCOS). Genome-wide association studies (GWAS) have been reported from various subpopulations to evaluate SNPs associated with PCOS risk. No PCOS-associated GWAS study… read more here.
Keywords: genome wide; risk; pcos; wide association ... See more keywords
Polycystic ovary syndrome: epidemiologic assessment of prevalence of systemic rheumatic and autoimmune diseases
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05850-0
Abstract: Polycystic ovary syndrome (PCOS) causes anovulation and hyperandrogenism. Hormonal imbalance is known to contribute to systemic autoimmune diseases. To examine the frequency of certain rheumatic diseases in PCOS. This retrospective study utilized and analyzed electronic… read more here.
Keywords: pcos; autoimmune diseases; ovary syndrome; polycystic ovary ... See more keywords
Upregulation of PD-L1 contributes to improving the apoptosis of granulosa cells via the PI3K/AKT pathway in PCOS
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DOI: 10.1007/s10815-024-03327-y
Abstract: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility and closely correlated with apoptosis in ovarian granulosa cells (GCs). Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway plays an important role throughout… read more here.
Keywords: gcs; pcos; pathway; pi3k akt ... See more keywords