Conversion of Classical and 11-oxygenated Androgens by Insulin Induced AKR1C3 in a Model of Human PCOS Adipocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac068
Abstract: Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women. A common symptom of PCOS is hyperandrogenism (AE); however, the source of these androgens is uncertain. Aldo-keto reductase family 1 member C3 (AKR1C3) catalyzes… read more here.
Keywords: oxygenated androgens; conversion classical; pcos; classical oxygenated ... See more keywords
Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqad033
Abstract: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. In PCOS, insulin resistance and hyperandrogenism could drive the increased risk for cardio-metabolic disease. Aldo-keto reductase family 1 member C3 (AKR1C3) is induced by… read more here.
Keywords: pcos adipocytes; acid synthase; pcos; akr1c3 ... See more keywords