LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "pcos mice" as a keyword



Long noncoding RNA NEAT1 decreases polycystic ovary syndrome progression via the modulation of the microRNA‐324‐3p and BRD3 axis

Sign Up to like & get
recommendations! Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11893

Abstract: Long noncoding RNA nuclear‐enriched abundant transcript 1 (NEAT1) is believed to be involved in many gynecological and obstetrics disorders. Nevertheless, the role of NEAT1 in polycystic ovary syndrome (PCOS) is scarcely investigated. Our study aimed… read more here.

Keywords: pcos mice; neat1; long noncoding; 324 brd3 ... See more keywords

PDE4 inhibitor Roflumilast modulates inflammation and lipid accumulation in PCOS mice to improve ovarian function and reduce DHEA‐induced granulosa cell apoptosis in vitro

Sign Up to like & get
recommendations! Published in 2023 at "Drug Development Research"

DOI: 10.1002/ddr.22027

Abstract: This study was implemented to address the role of Roflumilast in polycystic ovary syndrome (PCOS) as well as to discuss its reaction mechanism in vivo and in vitro. In vivo, mice were administrated with 6 mg… read more here.

Keywords: dhea induced; pcos mice; lipid accumulation; mice ... See more keywords

Diacerein mitigates endocrine and cardio-metabolic disruptions in experimental PCOS mice model by modulating AdipoR1/ PON 1

Sign Up to like & get
recommendations! Published in 2024 at "BMC Endocrine Disorders"

DOI: 10.1186/s12902-024-01639-9

Abstract: This study aimed to explore the impact of Diacerein (DIC) on endocrine and cardio-metabolic changes in polycystic ovarian syndrome (PCOS) mouse model. A total of 18 adult female mice (Parkes strain), aged 4–5 weeks, were… read more here.

Keywords: pcos mice; cardio metabolic; endocrine cardio; model ... See more keywords

MON-231 Dietary Interventions Can Ameliorate Polycystic Ovary Syndrome (PCOS) Traits in a PCOS Mouse Model

Sign Up to like & get
recommendations! Published in 2019 at "Journal of the Endocrine Society"

DOI: 10.1210/js.2019-mon-231

Abstract: Abstract Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder characterized by reproductive, endocrine and metabolic abnormalities; however, its aetiology is unknown and current medical management relies solely on symptomatic treatment. Hyperandrogenism is a defining… read more here.

Keywords: mice; pcos; dietary interventions; polycystic ovary ... See more keywords

E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism

Sign Up to like & get
recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1137089

Abstract: Objective Gut microbiota and its metabolites have regulatory effects on PCOS related ovarian dysfunction and insulin resistance. Escherichia coli Nissle 1917 (EcN) is a genetically controlled probiotic with an excellent human safety record for improving… read more here.

Keywords: metabolism; gut; pcos mice; gut microbiota ... See more keywords