84 Participants with T2DM have improved cardiac function with fatty acid metabolism, despite unchanged cardiac energetics
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DOI: 10.1136/heartjnl-2020-bcs.84
Abstract: Background/Introduction The Phosphocreatine-to-Adenosine Triphosphate ratio (PCr/ATP) is an established indicator of cardiac energetic status. Measurement of the Creatine Kinase pseudo-first order rate constant (CKkf) provides a more sensitive measure of cardiac energetics, and allows calculation… read more here.
Keywords: cardiac energetics; pcr atp; participants t2dm; ins dex ... See more keywords
Increased cardiac Pi/PCr in the diabetic heart observed using phosphorus magnetic resonance spectroscopy at 7T
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DOI: 10.1371/journal.pone.0269957
Abstract: Phosphorus magnetic resonance spectroscopy (31P-MRS) has previously demonstrated decreased energy reserves in the form of phosphocreatine to adenosine-tri-phosphate ratio (PCr/ATP) in the hearts of patients with type 2 diabetes (T2DM). Recent 31P-MRS techniques using 7T… read more here.
Keywords: spectroscopy; pcr atp; cardiac pcr; heart ... See more keywords
Cardiac energy metabolism is decreased in male volunteers with prediabetes and does not normalize during the day
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DOI: 10.14814/phy2.70242
Abstract: Type 2 diabetes mellitus is characterized by a low cardiac energy status (PCr/ATP ratio), but it is unknown whether this also applies to prediabetes. Since PCr/ATP is correlated with elevated free fatty acids (FFA), a… read more here.
Keywords: pcr atp; energy status; male volunteers; cardiac energy ... See more keywords
Cardiac Energetics Before, During and After Anthracycline-based Chemotherapy in Breast Cancer Patients Using 31P Magnetic Resonance Spectroscopy: A Pilot Study
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DOI: 10.21203/rs.3.rs-114644/v1
Abstract: PURPOSETo explore the utility of phosphorus magnetic resonance spectroscopy (31P MRS) in identifying anthracycline-induced cardiac toxicity in patients with breast cancer.METHODS20 patients with newly diagnosed breast cancer receiving anthracycline-based chemotherapy had cardiac magnetic resonance assessment… read more here.
Keywords: pcr atp; chemo; magnetic resonance; breast cancer ... See more keywords