PCSK6 and Survival in Idiopathic Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1101/2022.05.06.22274705
Abstract: Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by limited treatment options and high mortality. Novel therapies and prognostic biomarkers are needed. Objective: To identify and validate molecular determinants of IPF survival. Methods:… read more here.
Keywords: idiopathic pulmonary; survival; genome wide; pcsk6 ... See more keywords
PCSK6 mediates Th1 differentiation and promotes chronic colitis progression and mucosal barrier injury via STAT1.
Sign Up to like & getrecommendations! Published in 2023 at "Aging"
DOI: 10.18632/aging.204739
Abstract: This study was aimed at investigating the expression and role of proprotein convertase subtilisin/kexin type (PCSK6) in inflammatory bowel disease (IBD). DSS induced mouse colitis and mucosal barrier injury, down-regulation of TJ proteins, improvement of… read more here.
Keywords: mucosal barrier; chronic colitis; barrier injury; pcsk6 ... See more keywords