Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide.
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DOI: 10.1021/jacs.2c08029
Abstract: Optimization of peptide stability is essential for the development of peptides as bona fide alternatives to approved monoclonal antibodies. This is clearly the case for the many peptides reported to antagonize proprotein convertase subtilisin-like/kexin type… read more here.
Keywords: improving stability; activity; pcsk9 inhibitory; stability ... See more keywords