Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30025
Abstract: Proprotein convertase subtilisin/kexin type‐9 (PCSK9), a member of the proprotein convertase family, is an important drug target because of its crucial role in lipid metabolism. Emerging evidence suggests a direct role of localized PCSK9 in… read more here.
Keywords: vascular disease; physiology; role; pcsk9 ... See more keywords
Effect of PCSK9 on Vascular Smooth Muscle Cell Functions: A New Player in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666210531150302
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secretory serine protease that plays multiple biological functions in the regulation of physiological and pathological processes. PCSK9 inhibitors decrease the circulating LDL-cholesterol level with well-known preventive and… read more here.
Keywords: vascular smooth; effect; smooth muscle; pcsk9 ... See more keywords