Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family
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DOI: 10.3390/ijms232314834
Abstract: The PCTAIRE subfamily belongs to the CDK (cyclin-dependent kinase) family and represents an understudied class of kinases of the dark kinome. They exhibit a highly conserved binding pocket and are activated by cyclin Y binding.… read more here.
Keywords: family; kinase; amino pyrazole; discovery amino ... See more keywords