Development of a differential multiplex real-time PCR assay for porcine circovirus type 2 (PCV2) genotypes PCV2a, PCV2b and PCV2d
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2020.113971
Abstract: A multiplex quantitative real-time polymerase chain reaction (mqPCR) assay was developed and validated for detection and differentiation of porcine circovirus type 2 (PCV2) genotypes, PCV2a, PCV2b and PCV2d. Single nucleotide polymorphism in primers or probes… read more here.
Keywords: pcv2a pcv2b; real time; pcv2; porcine circovirus ... See more keywords
Molecular detection of Hsp90 inhibitor suppressing PCV2 replication in host cells.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2019.04.037
Abstract: Porcine Circovirus Type 2 (PCV2) is a pathogen that has the ability to cause devastating disease manifestations in pig populations with major economic implications. Our previous research found that Hsp90 is required for PCV2 production… read more here.
Keywords: hsp90; pcv2; host cells; pcv2 replication ... See more keywords
Markedly different immune responses and virus kinetics in littermates infected with porcine circovirus type 2 or porcine parvovirus type 1.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.08.003
Abstract: Porcine parvovirus type 1 (PPV1) and porcine circovirus type 2 (PCV2) are small single-stranded DNA viruses with high prevalence in the global pig population. The aim of this study was to compare and contrast PCV2… read more here.
Keywords: response; pcv2; porcine; type ... See more keywords
Efficient production and characterization of immunogenic HEV-PCV2 chimeric virus-like particles.
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2022.109410
Abstract: Zoonotic hepatitis E virus (HEV) infection is an emerging global public health concern. It is usually transmitted to humans from domestic pigs (main host). Since virus-like particles (VLPs) exhibit unique structural and immunological characteristics that… read more here.
Keywords: hev; hev pcv2; pcv2; production ... See more keywords
Genotypic diversity of porcine circovirus type 2 (PCV2) and genotype shift to PCV2d in Korean pig population.
Sign Up to like & getrecommendations! Published in 2017 at "Virus research"
DOI: 10.1016/j.virusres.2016.11.015
Abstract: Porcine circovirus type 2 (PCV2) is a causative agent of PCV2-associated disease (PCVAD), which leads to enormous economic losses in the swine industry worldwide. A high nucleotide substitution rate allows for the continuous evolution of… read more here.
Keywords: genotype shift; diversity; pcv2; shift pcv2d ... See more keywords
Immunomodulatory and antioxidant effects of total flavonoids of Spatholobus suberectus Dunn on PCV2 infected mice
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09340-9
Abstract: Oxidative stress plays an important role in the pathogenesis of virus infection and antioxidants are becoming promising candidates as therapeutic agents. This study is designed to investigate the effect of total flavonoids of Spatholobus suberectus Dunn… read more here.
Keywords: pcv2; oxidative stress; total flavonoids; flavonoids spatholobus ... See more keywords
Selection of affinity peptides for the purification potential of porcine circovirus type 2 (PCV2) Cap virus-like particles (VLPs)
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra05790c
Abstract: In this study, we describe the use of a M13 phage-displayed random peptide library for screening novel peptide motifs that specifically recognize recombinant PCV2 Cap protein for the first time. The peptide had a sequence… read more here.
Keywords: pcv2; pcv2 cap; affinity peptides; selection affinity ... See more keywords
Development of a loop-mediated isothermal amplification (LAMP) assay for rapid visual detection of porcine circovirus type 2 (PCV2) and its application.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2095516
Abstract: A cost effective, simple and rapid method is critical for detection of porcine circovirus type 2 (PCV2) infection in pigs. The present study reports the development and evaluation a loop-mediated isothermal amplification (LAMP) assay for… read more here.
Keywords: pcv2; visual detection; lamp assay; detection porcine ... See more keywords
Genetic analysis of porcine circovirus type 2 (PCV2) in Queensland, Australia.
Sign Up to like & getrecommendations! Published in 2020 at "Australian veterinary journal"
DOI: 10.1111/avj.12952
Abstract: OBJECTIVE To determine the current porcine circovirus type 2 (PCV2) genotypes circulating in pigs in Queensland (QLD). METHODS The PCV2 infection status of pigs was determined by real-time PCR testing of 210 lymph nodes and… read more here.
Keywords: circovirus type; pcv2; analysis; porcine circovirus ... See more keywords
Emergence of a Novel Recombinant Porcine Circovirus type 2 in China: PCV2c and PCV2d recombinant.
Sign Up to like & getrecommendations! Published in 2019 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.13307
Abstract: Porcine circovirus type 2 (PCV2) has been causing huge economic losses in Chinese swine herds since it was first identified in China in 1999. Genotypes of PCV2 except for PCV2c coexist in swine herds in… read more here.
Keywords: circovirus type; pcv2; analysis; porcine circovirus ... See more keywords
PCV2 Induces Reactive Oxygen Species To Promote Nucleocytoplasmic Translocation of the Viral DNA Binding Protein HMGB1 To Enhance Its Replication
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.00238-20
Abstract: Porcine circovirus type 2 (PCV2) is a small DNA virus that depends heavily on host cells for its infection. This study reports the close relationship between subcellular localization of host high-mobility-group box 1 (HMGB1) protein… read more here.
Keywords: translocation; replication; pcv2; infection ... See more keywords