Porcine circovirus type 2 exploits cap to inhibit PKR activation through interaction with Hsp40.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2020.108929
Abstract: Porcine circovirus type 2 is the main pathogen of porcine circovirus disease, which has caused enormous economic losses to the pig industry worldwide. The PKR signaling pathway is important for the cellular antiviral response, but… read more here.
Keywords: dnajc7; pcv2 infection; porcine circovirus;
Glutamine Deficiency Promotes PCV2 Infection through Induction of Autophagy via Activation of ROS-Mediated JAK2/STAT3 Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b04704
Abstract: Porcine circovirus type 2 (PCV2) is an important pathogen in swine herds. We previously reported that glutamine (Gln) deficiency promoted PCV2 infection in vitro. Here, we established a Gln deficiency model in vivo and further… read more here.
Keywords: gln deficiency; pcv2 infection; deficiency; jak2 stat3 ... See more keywords
The gC1qR Binding Site Mutant PCV2 Is a Potential Vaccine Strain That Does Not Impair Memory CD4+ T-Cell Generation by Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00959-22
Abstract: PCV2 is one of the costliest pathogens in pigs worldwide. Usage of PCV2 vaccines can prevent the PCV2 infection-induced clinical syndromes but not the viral spread. ABSTRACT PCV2 has been reported to reduce the protective… read more here.
Keywords: memory cd4; infection; pcv2 infection; pcv2 ... See more keywords
The effect of Panax notoginseng saponins on oxidative stress induced by PCV2 infection in immune cells: in vitro and in vivo studies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.2020.21.e61
Abstract: Background Panax notoginseng saponins (PNS) are bioactive substances extracted from P. notoginseng that are widely used to treat cardiovascular and cerebrovascular diseases and interstitial diseases. PNS have the functions of scavenging free radicals, anti-inflammation, improving… read more here.
Keywords: pcv2 infection; vitro vivo; stress; immune cells ... See more keywords