Cost-effectiveness of PCV20 to Prevent Pneumococcal Disease in the Pediatric Population: A German Societal Perspective Analysis
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DOI: 10.1007/s40121-024-00977-4
Abstract: Since 2009, a pneumococcal conjugate vaccine (PCV) covering 13 serotypes (PCV13) has been included by Germany’s Standing Committee on Vaccinations for infants, resulting in major reductions in pneumococcal disease (PD). Higher-valent vaccines may further reduce… read more here.
Keywords: pneumococcal conjugate; disease; pcv20; conjugate vaccine ... See more keywords
Economic Evaluation of Transitioning to the 20-Valent Pneumococcal Conjugate Vaccine in the Dutch Paediatric National Immunisation Programme
Sign Up to like & getrecommendations! Published in 2025 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-025-01109-2
Abstract: In 2024, the vaccination strategy against pneumococcal disease in the Dutch paediatric population was changed from the 10-valent pneumococcal conjugate vaccine (PCV) (PCV10) to a 15-valent PCV (PCV15) under a 2 + 1 schedule. We aimed to… read more here.
Keywords: disease; pcv20; pcv15; dutch paediatric ... See more keywords
The 20-valent pneumococcal conjugate vaccine (PCV20): expected added value
Sign Up to like & getrecommendations! Published in 2022 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2022.2039865
Abstract: ABSTRACT Objectives Currently existing pneumococcal vaccines have contributed to a major reduction in pneumococcal disease. However, there remains an unmet need for vaccine coverage of serotypes not included in PCV13 to further reduce the burden… read more here.
Keywords: valent pneumococcal; pcv20; disease; pneumococcal disease ... See more keywords
1236. Safety and Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine (PCV20) in Healthy Infants in the United States
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DOI: 10.1093/ofid/ofaa439.1421
Abstract: A 20-valent pneumococcal conjugate vaccine (PCV20) is being developed to extend protection against pneumococcal disease beyond that of the 13-valent pneumococcal vaccine (PCV13). This is the first safety and immunogenicity study of PCV20 in healthy… read more here.
Keywords: research; pfizer; pcv20; pfizer employee ... See more keywords
P-58. Quantifying the impact of introducing a new adult-focused PCV in the United States
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DOI: 10.1093/ofid/ofae631.265
Abstract: Abstract Background In the United States, pneumococcal conjugate vaccines (PCVs) were first recommended for use in children in 2000, and approximately 82% currently receive the full 3+1 schedule. As of May 2024, adults aged 65… read more here.
Keywords: united states; pcv20; phd merck; merck inc ... See more keywords
Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs
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DOI: 10.1371/journal.pone.0281261
Abstract: Introduction Two next-generation pneumococcal conjugate vaccines (PCVs), a 15- and a 20-valent PCV (PCV15 and PCV20), have recently been licensed for use in adults, and PCV15 has also been licensed in children. We developed a… read more here.
Keywords: pcv13; pcv20; next generation; ipd ... See more keywords
Higher valency vaccines’ impact on antimicrobial resistance rates in Streptococcus pneumoniae causing invasive disease: a retrospective analysis based on national reference laboratory data, Belgium, 2018 to 2023
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DOI: 10.2807/1560-7917.es.2025.30.45.2500179
Abstract: BACKGROUND Fifteen- and 20-valent pneumococcal conjugate vaccines (PCVs) offer broader protection against invasive pneumococcal disease (IPD) than PCV13. Adopting these vaccines may result in decreasing IPD incidence, antibiotic use and antimicrobial resistance (AMR) rates. If… read more here.
Keywords: resistance; retrospective analysis; pcv20; non pcv13 ... See more keywords