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   Articles with "pcz" as a keyword



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In Vitro and In Vivo Study on the Toxic Effects of Propiconazole Fungicide in the Pathogenesis of Liver Fibrosis.

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recommendations! Published in 2021 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.1c01086

Abstract: Propiconazole (PCZ) is a hepatotoxic triazole fungicide. There are insufficient data on how PCZ induces liver fibrosis in humans. This study aimed to investigate the effect of PCZ on liver fibrosis and its underlying mechanisms.… read more here.

Keywords: pcz; vivo study; vitro vivo; liver fibrosis ... See more keywords

Development of posaconazole nanocrystalline solid dispersion: preparation, characterization and in vivo evaluation

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recommendations! Published in 2024 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2024.2353314

Abstract: Abstract Objective Posaconazole (PCZ) is an antifungal drug, which acts by inhibiting the lanosterol-14α-demethylase enzyme. It is a biopharmaceutical classification system class II drug with its bioavailability being limited by poor aqueous solubility. The aim… read more here.

Keywords: pcz; preparation; solid dispersion; nanocrystalline solid ... See more keywords

Supercapacitor device performances of polycarbazole/graphene and polycarbazole/nanoclay/graphene nanocomposites

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recommendations! Published in 2018 at "Plastics, Rubber and Composites"

DOI: 10.1080/14658011.2018.1463687

Abstract: ABSTRACT In this study, graphene oxide (GO) is chemically reacted with sodium borohydride (NaBH4) to form reduced graphene oxide (rGO). rGO, polycarbazole (PCz)/rGO and PCz/nanoclay/rGO materials were obtained by chemical polymerisation method. These three materials… read more here.

Keywords: rgo; pcz; polycarbazole; nanoclay ... See more keywords

Elimination of antibiotic contaminants from wastewater using polycarbazole nanocomposites as microwave-activated catalysts

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recommendations! Published in 2024 at "Nanotechnology"

DOI: 10.1088/1361-6528/ada1dd

Abstract: Ciprofloxacin (CIP) is a widely used antibiotic, and its presence in water bodies poses a risk due to its resistance to conventional wastewater treatment processes. The accumulation of such pharmaceuticals can disrupt aquatic ecosystems, harm… read more here.

Keywords: degradation; pcz; pcz ppy; min ... See more keywords

An Insight into the Endophytic Bacterial Community of Tomato after Spray Application of Propiconazole and Bacillus subtilis Strain NBRI-W9

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recommendations! Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.01186-22

Abstract: Endophytes are plant inhabitants acting as its extended genome. The present study highlights the importance of maintaining plant endophytes for sustainable disease resistance in plants. ABSTRACT Propiconazole (PCZ) is a commonly sprayed fungicide against fungal… read more here.

Keywords: application; disease; pcz; tomato ... See more keywords
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Inhibition of circulating dipeptidyl-peptidase 3 restores cardiac function in a sepsis-induced model in rats: A proof of concept study

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recommendations! Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0238039

Abstract: Sepsis is a global economic and health burden. Dipeptidyl peptidase 3 (DPP3) is elevated in the plasma of septic patients. The highest levels of circulating DPP3 (cDPP3) are found in non-survivor septic shock patients. The… read more here.

Keywords: sepsis; pcz; cardiac function; group ... See more keywords
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Deciphering the Relationship Between the Trough Concentration of Posaconazole and Its Efficacy and Safety in Chinese Patients With Hematological Disorders

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recommendations! Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.575463

Abstract: Posaconazole (PCZ) is effective in preventing and salvage treatment invasive fungal infections in patients with hematologic disorders. However, PCZ displays highly variable individual pharmacokinetics affecting its efficacy and safety. To investigate the correlation between PCZ… read more here.

Keywords: cmin; pcz; efficacy safety; efficacy ... See more keywords

Dose Optimisation of Posaconazole and Therapeutic Drug Monitoring in Pediatric Patients

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.833303

Abstract: Experience in the clinical use of posaconazole (PCZ) in pediatric patients is limited, and no specific dose recommendations exist. This study aimed to investigate an appropriate dosing regimen, and assess the exposure-response relationships of PCZ… read more here.

Keywords: dose optimisation; pcz; pcz concentrations; optimisation posaconazole ... See more keywords