An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics
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DOI: 10.1007/s13346-020-00758-9
Abstract: PD98059 is a reversible MEK inhibitor that we are investigating as a potential treatment for neurochemical changes in the brain that drive neurohumoral excitation in heart failure. In a rat model that closely resembles human… read more here.
Keywords: pd98059; mek inhibitor; heart failure; release ... See more keywords