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A Bioinspired Manganese-Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes.

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Published in 2023 at "Advanced science"

DOI: 10.1002/advs.202206854

Abstract: Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients. Nanozyme-based antioxidants are emerging to treat stroke through scavenging excessive ROS. However,… read more here.

Keywords: endogenous antioxidant; organic framework; manganese organic; antioxidant enzymes ... See more keywords