Abstract B106: Elucidating the clonal dynamics and epigenetic regulators of PDAC initiation in inducible neoplastic organoid models
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DOI: 10.1158/1538-7445.pancreatic25-b106
Abstract: Pancreatic intraepithelial neoplasms (PanINs), precursor lesions of pancreatic ductal adenocarcinoma (PDAC) that are abundant healthy individuals, rarely progress to cancer despite universally possessing many of the driver alterations associated with malignancy. Recent single cell profiling… read more here.
Keywords: cancer; clonal dynamics; pdac initiation; elucidating clonal ... See more keywords