Dysbindin promotes pancreatic ductal adenocarcinoma metastasis by activating NF-κB/MDM2 via miR-342-3p.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.02.033
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the most invasive solid tumours and has the highest cancer-related mortality rate. Despite intense investigation, the molecular mechanisms underlying the invasiveness and aetiology of PDAC remain elusive. MicroRNAs… read more here.
Keywords: mir 342; metastasis; dysbindin; pancreatic ductal ... See more keywords
Epigenomic Changes Prime PDAC Metastasis.
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DOI: 10.1158/2159-8290.cd-nb2017-025
Abstract: Widespread chromatin modifications and DNA methylation could be responsible for inducing the spread of pancreatic ductal adenocarcinoma cells to distant sites, according to recent research. The findings also implicate glucose metabolism as a driver of… read more here.
Keywords: epigenomic changes; changes prime; metastasis; prime pdac ... See more keywords