Early Aβ-HBc virus-like particles immunization had better effects on preventing the deficit of learning and memory abilities and reducing cerebral Aβ load in PDAPP mice.
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DOI: 10.1016/j.vaccine.2018.07.049
Abstract: For nearly two decades, immunization against the β-amyloid peptide (Aβ) has been investigated as a potential treatment for Alzheimer's disease (AD). Despite some disappointing results in clinic trials, greater significance has been attached by some… read more here.
Keywords: hbc vlps; memory abilities; pdapp mice; learning memory ... See more keywords