PDB_Amyloid: an extended live amyloid structure list from the PDB
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12524
Abstract: The Protein Data Bank (PDB) contains more than 135 000 entries at present. From these, relatively few amyloid structures can be identified, since amyloids are insoluble in water. Therefore, most amyloid structures deposited in the… read more here.
Keywords: amyloid; pdb amyloid; amyloid structures; pdb ... See more keywords
In vitro inhibitory effects of some acetophenone derivatives on some metabolic enzymes and molecular docking
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000210
Abstract: In this study, the acetophenone derivatives 1–6 were found to be effective inhibitor molecules for α‐glycosidase, human carbonic anhydrases I and II (hCA I/II), and acetylcholinesterase (AChE), with Ki values in the range of 167.98 ± 25.06… read more here.
Keywords: inhibitory effects; vitro inhibitory; acetophenone derivatives; pdb ... See more keywords
Se⋅⋅⋅O/S and S⋅⋅⋅O Chalcogen Bonds in Small Molecules and Proteins: A Combined CSD and PDB Study
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DOI: 10.1002/cbic.202100498
Abstract: The importance of selenium‐centered noncovalent chalcogen bonds represented as Se⋅⋅⋅A (A=O/S) has been explored for short directional contacts in small molecules and proteins. In addition, S⋅⋅⋅O centered contacts have been analyzed. Computational analyses involving the… read more here.
Keywords: pdb; molecules proteins; chalcogen bonds; small molecules ... See more keywords
Mutations in Profilin 1 Cause Early‐Onset Paget's Disease of Bone With Giant Cell Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4275
Abstract: Paget's disease of bone (PDB) is a late‐onset chronic progressive bone disease characterized by abnormal activation of osteoclasts that results in bone pain, deformities, and fractures. PDB is very rare in Asia. A subset of… read more here.
Keywords: bone; pdb; early onset; pdb gct ... See more keywords
A Mechanism for the Activation of the Influenza Virus Transcriptase
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cell"
DOI: 10.1016/j.molcel.2018.10.005
Abstract: (Molecular Cell 70, 1101–1110.e1–e4; June 21, 2018) In the originally published article, one of the PDB ID numbers shown in the Key Resources Table and in the STAR Methods under Data and Software Availability was… read more here.
Keywords: mechanism activation; virus transcriptase; pdb; activation influenza ... See more keywords
Molecular insights into an ancient form of Paget’s disease of bone
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1820556116
Abstract: Significance We identify an ancient and atypical form of Paget’s disease of bone (PDB) in a collection of medieval skeletons exhibiting unusually extensive pathological changes, high disease prevalence, and low age-at-death estimations. Proteomic analysis of… read more here.
Keywords: disease bone; form paget; disease; pdb ... See more keywords
RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1004
Abstract: Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania and makes 3D… read more here.
Keywords: data bank; research; pdb; rcsb ... See more keywords
pdb-tools: a swiss army knife for molecular structures
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DOI: 10.12688/f1000research.17456.1
Abstract: The pdb-tools are a collection of Python scripts for working with molecular structure data in the Protein Data Bank (PDB) format. They allow users to edit, convert, and validate PDB files, from the command-line, in… read more here.
Keywords: army knife; swiss army; tools swiss; pdb ... See more keywords
miR-16 is highly expressed in Paget's associated osteosarcoma.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine-related cancer"
DOI: 10.1530/erc-16-0487
Abstract: Bone is an endocrine organ that produces key hormones and cytokines (Green et al. 2015b). Paget’s disease of bone (PDB) is a polygenic disorder of bone turnover first described by Sir James Paget in 1876.… read more here.
Keywords: tissue; bone; pdb; paget ... See more keywords
Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
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DOI: 10.3389/fcell.2022.903612
Abstract: Background: Paget’s disease of bone (PDB) is characterized by focal areas of dysregulated bone turnover resulting in increased bone loss and abnormal bone formation with variable severity. PDB has a complex etiology and both genetics… read more here.
Keywords: pdb; disease; bone; dna methylation ... See more keywords
Update on the pathogenesis and genetics of Paget’s disease of bone
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.932065
Abstract: Studies over the past two decades have led to major advances in the pathogenesis of Paget’s disease of bone (PDB) and particularly on the role of genetic factors. Germline mutations of different genes have been… read more here.
Keywords: pdb; disease bone; pathogenesis; biology ... See more keywords