Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis
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DOI: 10.1080/2162402x.2018.1445949
Abstract: ABSTRACT Multiple non-redundant immunosuppressive pathways co-exist in the tumor microenvironment and their co-targeting can increase clinical responses. Indeed, concurrent blockade of CTLA-4 and PD-1 in patients with advanced melanoma increased clinical responses over monotherapy alone… read more here.
Keywords: tigit cd96; cd96; pdcd1 cd96; cd96 mice ... See more keywords