High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer
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DOI: 10.1080/2162402x.2017.1390640
Abstract: ABSTRACT DNA mismatch repair (MMR)-deficient cancers accumulate high numbers of coding microsatellite mutations, which lead to the generation of highly immunogenic frameshift peptide (FSP) neoantigens. MMR-deficient cells can grow out to clinically manifest cancers either… read more here.
Keywords: pdcd1 positive; positive cell; cell; cell infiltration ... See more keywords