Articles with "pdcd5" as a keyword



Epigenetic Regulation of CD8+ Effector T Cell Differentiation by PDCD5

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Published in 2025 at "European Journal of Immunology"

DOI: 10.1002/eji.202451388

Abstract: Epigenetic modification plays a crucial role in establishing the transcriptional program that governs the differentiation of CD8+ effector T cells. However, the mechanisms by which this process is regulated at an early stage, prior to… read more here.

Keywords: differentiation; cd8; cd8 effector; pdcd5 ... See more keywords

The Effect of Global DNA Methylation on PDCD5 Expression in the PBMC of Occupational Chromate Exposed Workers.

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Published in 2021 at "Journal of occupational and environmental medicine"

DOI: 10.1097/jom.0000000000002192

Abstract: OBJECTIVES To evaluate the alteration of protein of programmed cell death 5 (PDCD5) in peripheral blood mononuclear cells (PBMC) and DNA methylation caused by hexavalent chromium exposure. METHODS There were 112 workers and 56 controls… read more here.

Keywords: pdcd5; dna; chromate exposed; dna methylation ... See more keywords

Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2a Protein

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Published in 2018 at "Hypertension"

DOI: 10.1161/hypertensionaha.118.11357

Abstract: PDCD5 (programmed cell death 5) is ubiquitously expressed in tissues, including the heart; however, the mechanism underlying the cardiac function of PDCD5 has not been understood. We investigated the mechanisms of PDCD5 in the pathogenesis… read more here.

Keywords: protein; cardiac hypertrophy; pdcd5; hypertrophy ... See more keywords

JMJD4 promotes tumor progression via inhibition of the PDCD5-TP53 pathway

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Published in 2024 at "BMB Reports"

DOI: 10.5483/bmbrep.2024-0027

Abstract: Programmed cell death 5 (PDCD5) regulates cell death and suppresses tumor progression. Since the stability and nuclear translocation of PDCD5 are regulated by TP53-dependent cell death stimuli, knowledge of the regulatory mechanism of PDCD5 function… read more here.

Keywords: cancer; tumor progression; jmjd4; pdcd5 ... See more keywords