Articles with "pdcov" as a keyword



Susceptibility to mice and potential evolutionary characteristics of porcine deltacoronavirus

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Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28048

Abstract: Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in suckling piglets and has the potential for cross‐species transmission, posing a threat to animal and human health. However, the susceptibility profile of different species… read more here.

Keywords: evolutionary characteristics; infected mice; porcine deltacoronavirus; susceptibility ... See more keywords

Genomic characterization and pathogenicity of porcine deltacoronavirus strain CHN-HG-2017 from China

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Published in 2018 at "Archives of Virology"

DOI: 10.1007/s00705-018-4081-6

Abstract: Porcine deltacoronavirus (PDCoV) was first detected in Hong Kong and has recently spread to many countries around the world. PDCoV causes acute diarrhea and vomiting in pigs, resulting in significant economic losses in the global… read more here.

Keywords: strain; porcine deltacoronavirus; pdcov; chn 2017 ... See more keywords

Study of the inhibitory effect of STAT1 on PDCoV infection

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Published in 2022 at "Veterinary Microbiology"

DOI: 10.1016/j.vetmic.2022.109333

Abstract: Porcine deltacoronavirus (PDCoV) is an enteropathogen found in many pig producing countries. It can cause acute diarrhea, vomiting, dehydration, and death in newborn piglets, seriously affecting the development of pig breeding industries. To date, our… read more here.

Keywords: pdcov infection; pdcov; llc pk1; study inhibitory ... See more keywords

A nucleic acid detection assay combining reverse transcription recombinase-aided amplification with a lateral flow dipstick for the rapid visual detection of porcine deltacoronavirus

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Published in 2022 at "Virulence"

DOI: 10.1080/21505594.2022.2116157

Abstract: ABSTRACT Porcine deltacoronavirus (PDCoV) is an emerging enteropathogen causing severe diarrhoea, dehydration, and death in nursing piglets and enormous economic losses for the global swine industry. Furthermore, it can infect multiple animal species including humans.… read more here.

Keywords: porcine deltacoronavirus; amplification; detection; nucleic acid ... See more keywords

Comprehensive analysis of codon usage pattern of porcine deltacoronavirus and its host adaptability.

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Published in 2022 at "Transboundary and emerging diseases"

DOI: 10.1111/tbed.14588

Abstract: The porcine deltacoronavirus (PDCoV) is a newly discovered pig enteric coronavirus that can infect cells from various species. In Haiti, PDCoV infections in children with acute undifferentiated febrile fever were recently reported. Considering the great… read more here.

Keywords: codon usage; porcine deltacoronavirus; analysis; gene ... See more keywords

HDAC6 Degrades nsp8 of Porcine Deltacoronavirus through Deacetylation and Ubiquitination to Inhibit Viral Replication

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Published in 2023 at "Journal of Virology"

DOI: 10.1128/jvi.00375-23

Abstract: As an emerging enteropathogenic coronavirus with zoonotic potential, porcine deltacoronavirus (PDCoV) has sparked tremendous attention. Histone deacetylase 6 (HDAC6) is a critical deacetylase with both deacetylase activity and ubiquitin E3 ligase activity and is extensively… read more here.

Keywords: hdac6; deacetylase; porcine deltacoronavirus; activity ... See more keywords

Serial cell culture passaging in vitro led to complete attenuation and changes in the characteristic features of a virulent porcine deltacoronavirus strain

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Published in 2024 at "Journal of Virology"

DOI: 10.1128/jvi.00645-24

Abstract: ABSTRACT Porcine deltacoronavirus (PDCoV) is an important enteric coronavirus that has caused enormous economic losses in the pig industry worldwide. However, no commercial vaccine is currently available. Therefore, developing a safe and efficacious live-attenuated vaccine… read more here.

Keywords: culture; live attenuated; porcine deltacoronavirus; pdcov ... See more keywords

GSDMD and GSDME exhibit distinct roles in enteric coronavirus PDCoV-induced pyroptosis and inflammatory responses

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Published in 2025 at "Journal of Virology"

DOI: 10.1128/jvi.01876-24

Abstract: ABSTRACT Porcine deltacoronavirus (PDCoV), an emerging enteric coronavirus with zoonotic potential, typically causes intestinal villous epithelial cell damage with inflammation. Pyroptosis is a recently identified inflammatory form of programmed cell death that has been found… read more here.

Keywords: induced pyroptosis; pyroptosis; pdcov induced; gsdmd ... See more keywords

NLRP1 restricts porcine deltacoronavirus infection via IL-11 inhibiting the phosphorylation of the ERK signaling pathway

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Published in 2024 at "Journal of Virology"

DOI: 10.1128/jvi.01982-23

Abstract: ABSTRACT Continuously emerging highly pathogenic coronaviruses remain a major threat to human and animal health. Porcine deltacoronavirus (PDCoV) is a newly emerging enterotropic swine coronavirus that causes large-scale outbreaks of severe diarrhea disease in piglets.… read more here.

Keywords: phosphorylation; erk signaling; infection; porcine deltacoronavirus ... See more keywords

Differential Susceptibility to Porcine Deltacoronavirus: Ducks Show Greater Vulnerability Than Geese

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Published in 2025 at "Transboundary and Emerging Diseases"

DOI: 10.1155/tbed/2339024

Abstract: Porcine deltacoronavirus (PDCoV), an enteropathogenic coronavirus belonging to the Deltacoronavirus genus, is globally distributed and represents a significant viral enteric disease in pigs. It primarily causes severe diarrhea in pigs, especially in newborn piglets, with… read more here.

Keywords: susceptibility; porcine deltacoronavirus; pdcov; shaoxing ducks ... See more keywords

Rapid and visual detection of porcine deltacoronavirus by recombinase polymerase amplification combined with a lateral flow dipstick

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Published in 2020 at "BMC Veterinary Research"

DOI: 10.1186/s12917-020-02341-3

Abstract: Background Porcine Deltacoronavirus (PDCoV) is a newly emerging Coronavirus that was first identified in 2012 in Hong Kong, China. Since then, PDCoV has subsequently been reported worldwide, causing a high number of neonatal piglet deaths… read more here.

Keywords: detection; lfd rpa; porcine; virus ... See more keywords