Plasmacytoid dendritic cells and type I interferons in flares of systemic lupus erythematosus triggered by COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology International"
DOI: 10.1007/s00296-021-04825-3
Abstract: We recently read with interest the article entitled “Can the SARS-CoV-2 infection trigger systemic lupus erythematosus? A case-based review” by Gracia-Ramos et al. [1]. The authors reviewed emerging cases of SARS-CoV-2 infection either flaring-up previously… read more here.
Keywords: sle; infection; type ifns; type ... See more keywords
Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.06.007
Abstract: Paracoccidioidomycosis (PCM) is a systemic mycosis caused by fungi from the genus Paracoccidioides in Latin America. PCM-patients (PCM-p) are classified as having acute/subacute or chronic (CF) clinical forms. CF is responsible for 75%-90% of all… read more here.
Keywords: paracoccidioidomycosis; cell; treatment; distribution ... See more keywords
Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2019.12.096
Abstract: Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are currently under evaluation for use in cancer vaccines. Although both DC subsets can activate adaptive and innate lymphocytes, their capacity to recruit such… read more here.
Keywords: human pdcs; melanoma patients; vaccination; cdc2s ... See more keywords
Easy detection of karlodinium veneficum using PCR-based dot chromatography strip.
Sign Up to like & getrecommendations! Published in 2020 at "Harmful algae"
DOI: 10.1016/j.hal.2020.101908
Abstract: In this study, a novel detection method by PCR-based dot chromatography strip (PDCS) is proposed. To investigate the application of PDCS in the detection of harmful microalgae, the internal transcribed spacer sequence of Karlodinium veneficum,… read more here.
Keywords: detection; based dot; strip; veneficum ... See more keywords
Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells.
Sign Up to like & getrecommendations! Published in 2022 at "Immunity"
DOI: 10.1016/j.immuni.2022.01.016
Abstract: Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs, comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We studied DC development in unmanipulated adult mice using inducible lineage tracing combined with… read more here.
Keywords: pdcs; clonal lineage; shared origin; dendritic cells ... See more keywords
Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian journal of gastroenterology"
DOI: 10.1080/00365521.2021.1974932
Abstract: BACKGROUND Poorly differentiated Clusters (PDCs) of tumor cells composed of more than five elements have been recently described in gastrointestinal cancers and correlate with a worse prognosis. Our study aims to investigate PDC occurrence in… read more here.
Keywords: poorly differentiated; gastric cancer; cancer; lymph node ... See more keywords
SAT0019 Tnf-Α regulates plasmacytoid dendritic cells by suppressing ifn-Α production and enhancing th1 and th17 cell differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4688
Abstract: Background Human plasmacytoid dendritic cells (pDCs) play a vital role in modulating immune responses. pDCs can produce massive amounts of type I IFNs in response to nucleic acids via toll-like receptors (TLRs) and they are… read more here.
Keywords: production; tnf; dendritic cells; plasmacytoid dendritic ... See more keywords
FRI0281 Transcriptomic profiling of pdcs from patients with pss identifies consistently altered gene networks that indicate an activated phenotype and enhanced anti-viral state
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6765
Abstract: Background Primary Sjögren’s syndrome is an autoimmune disease characterised by lymphocytic infiltration of the exocrine glands and dryness of mouth and eyes. Type-I interferons (IFN) are thought to play an important role in pSS pathogenesis… read more here.
Keywords: phenotype; patients pss; gene clusters; gene ... See more keywords
THU0028 AN EXPLANTION FOR HOW VIRAL INFECTION MAY TRIGGER SPONDYLOARTHROPATHY BASED ON TLR9 DRIVEN TNF RESPONSES FROM ENTHESEAL DERIVED PLASMACYTOID DENDRITIC CELLS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.5262
Abstract: It is well known that viral infections may trigger psoriatic arthritis (PsA), a disease that typically has extensive pre-clinical entheseal abnormalites. Skin resident plasmacytoid dendritic cells (pDCs) produce IFNα that contribute to T cell expansion… read more here.
Keywords: none; viral infection; none declared; pdcs ... See more keywords
Abstract 1912: Study on the role of targeting ERBB and its potential resistance mechanism in biliary tract cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-1912
Abstract: Purpose: Biliary tract cancer (BTC) is a kind of malignant digestive system tumors without a targeted drug approved in the clinic. A high proportion of gene mutations and abnormal expressions of ERBB pathway have been… read more here.
Keywords: targeting erbb; study; potential resistance; cancer ... See more keywords
CCR9 axis inhibition enhances hepatic migration of plasmacytoid DCs and protects against liver injury
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.159910
Abstract: Plasmacytoid dendritic cells (pDCs) perform dual proinflammatory and immunosuppressive roles. We recently reported the potential of pDC therapy for treatment of intractable acute liver failure. However, establishment of efficient methods to deliver pDCs to the… read more here.
Keywords: acute liver; ccr9 axis; pdcs; migration ... See more keywords