Stabilization of a stock‐loan valuation PDE process using differential flatness theory
Sign Up to like & getrecommendations! Published in 2019 at "Asian Journal of Control"
DOI: 10.1002/asjc.2129
Abstract: The article proposes flatness‐based control for stabilization of a stock‐loan valuation process that is described by a partial differential equation. By applying semi‐discretization and the finite differences method, the state‐space model of the stock loan… read more here.
Keywords: state; stock loan; pde; control ... See more keywords
Pyridoxine‐Dependent Epilepsy: A Treatable Epilepsy Syndrome Presenting with Dystonia and Congenital Cataracts with a Novel Mutation
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13651
Abstract: Pyridoxine-dependent epilepsy (PDE; MIM#266100), an early-onset epileptic encephalopathy, is an autosomal recessive inborn error of pyridoxine (vitamin B6) metabolism. PDE is due to mutations in the ALDH7A1 gene (MIM*107323) on chromo-some 5q31, fi rst described… read more here.
Keywords: dependent epilepsy; congenital cataracts; pde; epilepsy ... See more keywords
Lie Algebras of Slow Growth and Klein-Gordon PDE
Sign Up to like & getrecommendations! Published in 2018 at "Algebras and Representation Theory"
DOI: 10.1007/s10468-018-9794-4
Abstract: AbstractWe discuss the notion of characteristic Lie algebra of a hyperbolic PDE. The integrability of a hyperbolic PDE is closely related to the properties of the corresponding characteristic Lie algebra χ. We establish two explicit… read more here.
Keywords: lie; lie algebras; mathfrak mathbb; pde ... See more keywords
Channeling of cAMP in PDE-PKA Complexes Promotes Signal Adaptation.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.04.045
Abstract: Spatiotemporal control of the cAMP signaling pathway is governed by both hormonal stimulation of cAMP generation by adenylyl cyclases (activation phase) and cAMP hydrolysis by phosphodiesterases (PDEs) (termination phase). The termination phase is initiated by… read more here.
Keywords: camp; pde8 complex; pde; hydrolysis ... See more keywords
Phosphodiesterase 1 inhibition and molecular docking study of phytochemicals isolated from stem heartwood of Heterophragma adenophyllum Seem
Sign Up to like & getrecommendations! Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2020.08.013
Abstract: Abstract Heterophragma adenophyllum (Wall. ex G.Don) Seem belong to family Bignoniacea. To find a safe, effective and economical drugs candidate, the screening of chemical constituents for various biological actions is essential. The isolated compounds (1–3),… read more here.
Keywords: heterophragma adenophyllum; pde; molecular docking; adenophyllum ... See more keywords
Discovery of Novel Turn-On Fluorescent Probes for Detecting PDEδ Protein in Living Cells and Tumor Slices.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c00335
Abstract: The first small molecule fluorescent turn-on probes for detecting PDEδ protein were rationally designed, which showed reasonable fluo-rescent properties and can be applied into visualizing the PDEδ protein at the living cell and tissue levels.… read more here.
Keywords: pde protein; detecting pde; pde; probes detecting ... See more keywords
Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c00929
Abstract: KRAS-PDEδ protein-protein interaction represents an appealing target for cancer therapy. However, fast release of high-affinity inhibitors from PDEδ hampered drug binding affinity and antiproliferative activity. To overcome the limitations, the first proteolysis-targeting chimeric (PROTAC) small… read more here.
Keywords: colorectal cancer; pde degraders; pde; kras mutant ... See more keywords
Contribution of sewage to occurrence of phosphodiesterase-5 inhibitors in natural water
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89028-3
Abstract: Phosphodiesterase-5 inhibitors (PDE-5i, such as Sildenafil, Tadalafil and Vardenafil, mainly prescribed to treat erectile dysfunction) and their generic drug equivalents have been widely marketed and consumed in Korea. From the concentrations detected in wastewater, we… read more here.
Keywords: stps; water; pde; phosphodiesterase inhibitors ... See more keywords
Sampled-output observer design in the presence of nonlinear heat PDE sensor
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Control"
DOI: 10.1080/00207179.2020.1819567
Abstract: The problem of observer design is addressed for linear plants that are observed with heat PDE sensors, leading to a global system with ODE-PDE cascade structure. One novelty of the study is that th... read more here.
Keywords: output observer; heat pde; pde; sampled output ... See more keywords
Permitted Daily Exposure of the Androgen Receptor Antagonist Flutamide
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx135
Abstract: This report aims to determine the permitted daily exposure (PDE) of flutamide, an androgen receptor blocker, as directed by guideline EMA/CHMP/CVPM/SWP/169430/2012 that came into effect on June 2015. A literature review was conducted to identify… read more here.
Keywords: pde; daily exposure; androgen receptor; permitted daily ... See more keywords
PDE-Based Deployment of Multiagents Measuring Relative Position to One Neighbor
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Control Systems Letters"
DOI: 10.1109/lcsys.2022.3169999
Abstract: We develop a PDE-based approach to multi-agent deployment where each agent measures its relative position to only one neighbor. First, we show that such systems can be modeled by a first-order hyperbolic partial differential equation… read more here.
Keywords: one neighbor; relative position; agent; position one ... See more keywords