Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function
Sign Up to like & getrecommendations! Published in 2019 at "Stroke"
DOI: 10.1161/strokeaha.118.023664
Abstract: Background and Purpose— Acetylsalicylic acid and clopidogrel are the 2 main antithrombotic drugs for secondary prevention in patients with ischemic stroke (IS) without indication for anticoagulation. Because of their limited efficacy and potential side effects,… read more here.
Keywords: pde inhibitor; pde; platelet function;
The Association Between Phosphodiesterase-5 Inhibitors and Colorectal Cancer in a National Cohort of Patients
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DOI: 10.14309/ctg.0000000000000173
Abstract: INTRODUCTION: To examine the association between phosphodiesterase-5 (PDE-5) inhibitor use and incidence of colorectal cancer among patients with erectile dysfunction treated in the Veterans Affairs (VA) Healthcare System. METHODS: A retrospective cohort study using the… read more here.
Keywords: pde inhibitor; colorectal cancer; cohort; cancer ... See more keywords
Phosphodiesterase-4 Inhibition in Psoriasis
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DOI: 10.2147/ptt.s303634
Abstract: Abstract Psoriasis is a chronic immune-mediated inflammatory disorder. Phosphodiesterase-4 (PDE-4) is an enzyme that mediates inflammatory responses and plays a role in psoriasis pathogenesis. PDE-4 degrades its substrate cyclic adenosine monophosphate (cAMP) to adenosine monophosphate… read more here.
Keywords: pde; pde inhibitor; psoriasis; inhibition psoriasis ... See more keywords