PDE1 inhibitors: a review of the recent patent literature (2008-present)
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DOI: 10.1080/13543776.2022.2027910
Abstract: ABSTRACT Introduction PDE1 has been demonstrated to be a potential drug target for a variety of diseases, such as Alzheimer’s disease and cardiovascular disease. In the past decades, numerous PDE1 inhibitors with structural diversities have… read more here.
Keywords: pde1 inhibitors; pde1; inhibitors review; 2008 present ... See more keywords
Potent In Vitro Phosphodiesterase 1 Inhibition of Flavone Isolated from Pistacia integerrima Galls
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DOI: 10.1155/2022/6116003
Abstract: To prospect an isozyme-specific, effective inhibitor against the physiologically-crucial enzyme phosphodiesterase 1 (PDE1), phytochemicals from Pistacia integerrima galls were screened. The chloroform fraction of gall extract was subjected to column chromatographic which led to the… read more here.
Keywords: pde1; flavone; phosphodiesterase; compound ... See more keywords