Structural insight into selective phosphodiesterase 4B inhibitors: pharmacophore-based virtual screening, docking, and molecular dynamics simulations
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DOI: 10.1080/07391102.2016.1183520
Abstract: Phosphodiesterase (PDE4) is the predominantly expressing family of PDE enzyme in immune and inflammatory cells. Inhibition of PDE4 has been reported to suppress a diverse spectrum of inflammatory responses both in vitro and in vivo.… read more here.
Keywords: analysis; pde4b; pde4d; structure ... See more keywords