Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
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DOI: 10.1021/acs.biochem.8b00288
Abstract: Selected members of the large rolipram-related GEBR family of type 4 phosphodiesterase (PDE4) inhibitors have been shown to facilitate long-term potentiation and to improve memory functions without causing emetic-like behavior in rodents. Despite their micromolar-range… read more here.
Keywords: molecular bases; bases pde4d; gebr library; pde4d inhibition ... See more keywords