Adaptation of Listeria monocytogenes to perturbation of c-di-AMP metabolism underpins its role in osmoadaptation and identifies a fosfomycin uptake system.
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DOI: 10.1111/1462-2920.16084
Abstract: The human pathogen Listeria monocytogenes synthesizes and degrades c-di-AMP using the diadenylate cyclase CdaA and the phosphodiesterases PdeA and PgpH respectively. c-di-AMP is essential because it prevents the uncontrolled uptake of osmolytes. Here, we studied… read more here.
Keywords: pdea pgph; cdaa; listeria monocytogenes; amp metabolism ... See more keywords