Neuroprotective efficacy of the bacterial metabolite, prodigiosin, against aluminium chloride‐induced neurochemical alternations associated with Alzheimer's disease murine model: Involvement of Nrf2/HO‐1/NF‐κB signaling
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23718
Abstract: Prodigiosin (PDG) is a bacterial metabolite with numerous biological and pharmaceutical properties. Exposure to aluminium is considered a root etiological factor in the pathological progress of Alzheimer's disease (AD). Here, in this investigation, we explored… read more here.
Keywords: aluminium; aluminium chloride; alzheimer disease; pdg ... See more keywords
Definition and application of proximal-distal gradient finger perfusion in systemic sclerosis by laser speckle contrast analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Microvascular research"
DOI: 10.1016/j.mvr.2021.104307
Abstract: OBJECTIVE In patients with systemic sclerosis (SSc) the perfusion of the fingers shows an alteration of the physiological proximal-distal gradient (PDG). The aim of this study is to provide a generalizable definition of PDG, applying… read more here.
Keywords: systemic sclerosis; analysis; pdg; ssc ... See more keywords
Descriptive analysis of the relationship between progesterone and basal body temperature across the menstrual cycle
Sign Up to like & getrecommendations! Published in 2022 at "Steroids"
DOI: 10.1016/j.steroids.2022.108964
Abstract: OBJECTIVE Describe the relationship between basal body temperature (BBT) and pregnanediol-3 alpha-glucuronide (PDG, the urine metabolite of progesterone) across the menstrual cycle. DESIGN Observational study. SETTING Study carried out from 1996 to 1997 in eight… read more here.
Keywords: relationship; pdg; cycle; basal body ... See more keywords
Laser speckle contrast analysis predicts major vascular complications and mortality of patients with systemic sclerosis.
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DOI: 10.1093/rheumatology/keaa514
Abstract: OBJECTIVES The aim of study was to evaluate peripheral blood perfusion and the proximal-distal gradient (PDG) of the hands as biomarkers of SSc major vascular complications (digital ulcers, pulmonary arterial hypertension, scleroderma renal crisis) and… read more here.
Keywords: perfusion; analysis; mortality; major vascular ... See more keywords
Comparison of Pinoresinol and its Diglucoside on their ADME Properties and Vasorelaxant Effects on Phenylephrine-Induced Model
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DOI: 10.3389/fphar.2021.695530
Abstract: Pinoresinol (PINL) and pinoresinol diglucoside (PDG), two natural lignans found in Eucommia ulmoides Oliv. (Duzhong), have several pharmacological activities. However, there is no report available on their absorption, distribution, metabolism, and elimination (ADME) properties. Given… read more here.
Keywords: phenylephrine induced; vasorelaxant effects; pinl; adme properties ... See more keywords
Prodigiosin induced the caspase-dependent apoptosis in human chronic myelogenous leukemia K562 cell
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DOI: 10.4103/1735-5362.305186
Abstract: Background and purpose: Chronic myeloid leukemia (CML) as a myeloproliferative disease is characterized by increased cellularity of bone marrow. Implementing the latest treatment protocols is currently accompanied by serious and life-threatening side effects. There are… read more here.
Keywords: apoptosis; k562; prodigiosin; leukemia ... See more keywords