CRISPR/Cas9-mediated modification of the extreme C-terminus impairs PDGF-stimulated activity of Duox2
Sign Up to like & getrecommendations! Published in 2018 at "Biological Chemistry"
DOI: 10.1515/hsz-2017-0229
Abstract: Abstract Duox2 belongs to the large family of NADPH-oxidase enzymes that are implicated in immune response, vasoregulation, hormone synthesis, cell growth and differentiation via the regulated synthesis of H2O2 and reactive oxygen species. We and… read more here.
Keywords: pdgf stimulated; stimulated activity; crispr cas9; activity ... See more keywords
RAB11A aggravates PDGF-BB-stimulated proliferation, migration, and inflammation of airway smooth muscle cells via affecting the NF-κB and PI3K/AKT pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i4.635
Abstract: BACKGROUND Pediatric asthma is an usual disease and a kind of fearful health threat for children. Airway smooth muscle cells (ASMCs) with increased cell proliferation and migration abilities serve as important features in the progression… read more here.
Keywords: rab11a; pi3k akt; proliferation migration; proliferation ... See more keywords