The Sanger Mouse Genetics Project: Understanding Neonatal Lethality
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DOI: 10.1016/j.mod.2017.04.359
Abstract: multiple oxygen-independent factors promoting HIF-1α stabilization. In cancer, the Warburg effect/pseudohypoxia, a state characterized for a change from aerobic to anaerobic metabolism, can promote HIF-1α stabilization through PHDs inhibition by 2oxoglutarate reduction. In neural crest… read more here.
Keywords: stabilization; genetics; hif stabilization; pdgf1a ... See more keywords