Temporal, spatial, and phenotypical changes of PDGFRα expressing fibroblasts during late lung development.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.03.020
Abstract: Many studies have investigated the source and role of epithelial progenitors during lung development; such information is limited for fibroblast populations and their complex role in the developing lung. In this study, we characterized the… read more here.
Keywords: muscle; pdgfr fibroblasts; expression; pdgfr expressing ... See more keywords
TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.242297
Abstract: ABSTRACT Mesenchymal stromal cells (MSCs) are multipotent progenitors essential for organogenesis, tissue homeostasis, regeneration and scar formation. Tissue injury upregulates transforming growth factor β (TGF-β) signaling, which modulates myofibroblast fate, extracellular matrix remodeling and fibrosis.… read more here.
Keywords: expression; pdgfr fibroblasts; factor; tcf7l2 ... See more keywords