LAUSR

PDGFRA Antibody for Soft Tissue Sarcoma

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1 Published in 2017 at "Cell"

DOI: 10.1016/j.cell.2017.01.028

Abstract: Lartruvo (olaratumab) is a monoclonal antibody against the extracellular domain of PDGFRA. Olaratumab blocks ligand binding and thereby inhibits activation of PDGFRA kinase activity. Pre-clinically, this antibody inhibited PDGFRA-dependent tumor growth. In a randomized Phase… read more here.

Keywords: tissue sarcoma; soft tissue; pdgfra; antibody ... See more keywords