Detection of FIP1L1-PDGFRA fusion gene-positive cells in the skin lesion of a patient with hypereosinophilic syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llac112
Abstract: Hypereosinophilic syndrome (HES) is a heterogeneous group of diseases, characterized by persistent hypereosinophilia and end-organ damage. The FIP1L1-PDGFRA (F/P) fusion gene is found in 3-25% of patients with HES and is an oncogenic driver of… read more here.
Keywords: fusion; pdgfra fusion; hypereosinophilic syndrome; fusion gene ... See more keywords
FIP1L1-PDGFRA fusion gene in a patient with asthma and rhinitis
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-242096
Abstract: Eosinophilia in asthma or rhinitis is usually considered to be reactive to the allergic diseases. We report a 33-year-old man with asthma and rhinitis, and progressive hypereosinophilia. Fluorescence in situ hybridization analysis detected interstitial chromosomal… read more here.
Keywords: fip1l1 pdgfra; asthma rhinitis; pdgfra fusion; fusion gene ... See more keywords