Myeloid neoplasm with a novel cryptic PDGFRB rearrangement detected by next-generation sequencing.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2020.03.002
Abstract: Rearrangements of PDGFRB are defining cytogenetic abnormalities seen in "Myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRB" and are generally evident by common cytogenetic methods. Here we present an unique case in which karyotyping and… read more here.
Keywords: pdgfrb rearrangement; rearrangement detected; detected next; rearrangement ... See more keywords
Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor Molecular Case Studies"
DOI: 10.1101/mcs.a004440
Abstract: Infantile myofibromatosis (IM) is an aggressive neoplasm composed of myofibroblast-like cells in children. Although typically localized, it can also present as multifocal disease, which represents a challenge for effective treatment. IM has previously been linked… read more here.
Keywords: infantile myofibromatosis; pdgfrb rearrangement; pdgfrb; novel pdgfrb ... See more keywords
Myeloid/Lymphoid Neoplasm with PDGFRB Rearrangement with t(5;10)(q33;q22) Harboring a Novel Breakpoint of the CCDC6-PDGFRB Fusion Gene
Sign Up to like & getrecommendations! Published in 2019 at "Internal Medicine"
DOI: 10.2169/internalmedicine.3220-19
Abstract: Myeloid/lymphoid neoplasms with PDGFRB rearrangement are a distinct type of myeloid neoplasms that occur in association with rearrangement of PDGFRB at 5q32. The hematological features most often show prominent eosinophilia. We herein report a patient… read more here.
Keywords: pdgfrb fusion; pdgfrb rearrangement; fusion gene; myeloid lymphoid ... See more keywords